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ISBN10: 1265352267 | ISBN13: 9781265352264
Genetics: From Genes to Genomes
ISBN10: 1265352267
ISBN13: 9781265352264
By Michael Goldberg and Janice Fischer
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Genetics: From Genes to Genomes represents a new approach to an undergraduate course in genetics. It reflects the way the authors currently view the molecular basis of life. The textbook emphasizes both the core concepts of genetics and the cutting-edge discoveries, modern tools, and analytical methods that will keep the science of genetics moving forward.
PART I Basic Principles: How Traits Are Transmitted
1 Mendel’s Principles of Heredity
2 Extensions to Mendel’s Laws
3 Chromosomes and Inheritance
4 Sex Chromosomes
5 Linkage, Recombination, and Gene Mapping
PART II What Genes Are and What They Do
6 DNA Structure, Replication, and Recombination
7 Mutation
8 Using Mutations to Study Genes
9 Gene Expression: The Flow of Information from DNA to RNA to Protein
PART III Analysis of Genetic Information
10 Digital Analysis of DNA
11 Genome Annotation
12 Analyzing Genomic Variation
PART IV How Genes Travel on Chromosomes
13 The Eukaryotic Chromosome
14 Chromosomal Rearrangements
15 Ploidy
16 Bacterial Genetics
17 Organellar Inheritance
PART V How Genes Are Regulated
18 Gene Regulation in Prokaryotes
19 Gene Regulation in Eukaryotes
20 Epigenetics
PART VI Using Genetics
21 Manipulating the Genomes of Eukaryotes
22 Genetic Analysis of Development
23 The Genetics of Cancer
PART VII Beyond the Individual Gene and Genome
24 Variation and Selection in Populations
25 Genetic Analysis of Complex Traits
1 Mendel’s Principles of Heredity
2 Extensions to Mendel’s Laws
3 Chromosomes and Inheritance
4 Sex Chromosomes
5 Linkage, Recombination, and Gene Mapping
PART II What Genes Are and What They Do
6 DNA Structure, Replication, and Recombination
7 Mutation
8 Using Mutations to Study Genes
9 Gene Expression: The Flow of Information from DNA to RNA to Protein
PART III Analysis of Genetic Information
10 Digital Analysis of DNA
11 Genome Annotation
12 Analyzing Genomic Variation
PART IV How Genes Travel on Chromosomes
13 The Eukaryotic Chromosome
14 Chromosomal Rearrangements
15 Ploidy
16 Bacterial Genetics
17 Organellar Inheritance
PART V How Genes Are Regulated
18 Gene Regulation in Prokaryotes
19 Gene Regulation in Eukaryotes
20 Epigenetics
PART VI Using Genetics
21 Manipulating the Genomes of Eukaryotes
22 Genetic Analysis of Development
23 The Genetics of Cancer
PART VII Beyond the Individual Gene and Genome
24 Variation and Selection in Populations
25 Genetic Analysis of Complex Traits
About the Author
Michael Goldberg
Dr. Michael Goldberg is a professor at Cornell University, where he teaches introductory
genetics and human genetics. He was an undergraduate at Yale University
and received his Ph.D. in biochemistry from Stanford University. Dr. Goldberg performed
postdoctoral research at the Biozentrum of the University of Basel (Switzerland)
and at Harvard University, and he received an NIH Fogarty Senior International
Fellowship for study at Imperial College (England) and fellowships from the
Fondazione Cenci Bolognetti for sabbatical work at the University of Rome (Italy).
His current research uses the tools of Drosophila genetics and the biochemical analysis
of frog egg cell extracts to investigate the mechanisms that ensure proper cell
cycle progression and chromosome segregation during mitosis and meiosis.
Janice Fischer
Dr. Janice Fischer is a Professor at The University of Texas at Austin, where she isan award-winning teacher of genetics and Director of the Biology Instructional Office.She received her Ph.D. in biochemistry and molecular biology from HarvardUniversity, and did postdoctoral research at The University of California at Berkeleyand The Whitehead Institute at MIT. In her current research, Dr. Fischer usesDrosophila to examine the roles of ubiquitin and endocytosis in cell signaling duringdevelopment.
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