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Casarett & Doull's Toxicology: The Basic Science of Poisons, 9th Edition
Casarett & Doull's Toxicology: The Basic Science of Poisons, 9th Edition

Casarett & Doull's Toxicology: The Basic Science of Poisons, 9th Edition, 9th Edition

ISBN10: 1259863743 | ISBN13: 9781259863745
By Curtis Klaassen
© 2018

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* The estimated amount of time this product will be on the market is based on a number of factors, including faculty input to instructional design and the prior revision cycle and updates to academic research-which typically results in a revision cycle ranging from every two to four years for this product. Pricing subject to change at any time.

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Toxicology’s gold-standard text - completely updated to reflect the latest breakthroughs and discoveries 

A Doody’s Core Title for 2022! 

Casarett & Doull’s Toxicology: The Basic Science of Poisons, Ninth Edition equips you with an unsurpassed understanding of modern toxicology, including the key principles, concepts, mechanisms, chemical-specific toxicity, and modes of thought that are the foundation of the discipline. This trusted classic not only delivers a comprehensive review of the essential components of toxicology, it offers the most up-to-date, revealing, and in-depth look at the systemic responses of toxic substance available anywhere.

Casarett & Doull’s Toxicology: The Basic Science of Poisons, Ninth Edition is logically divided into seven sections:

  • General Principles of Toxicology
  • Disposition of Toxicants
  • Non-Organ Directed Toxicity
  • Target Organ Toxicity
  • Toxic Agents
  • Environmental Toxicology
  • Applications of Toxicology

Many new contributors capture the progress made in toxicology over the past few years:
This edition is markedly updated from the previous edition, with more than one-third of the chapters authored by scientists who have not made previous contributions to the book. 

Sharing their expertise, they deliver dynamic new coverage of the importance of apoptosis, autophagy, cytokines, growth factors, oncogenes, cell cycling, receptors, gene regulation, protective mechanisms, repair mechanisms, transcription factors, signaling pathways, transgenic mice, knock-out mice, humanized mice, polymorphisms, microarray technology, second-generation sequencing, genomics, proteomics, epigenetics, exposome, microbiota, read across, adverse outcome pathways, high-content screening, computational toxicology, innovative test methods, and organ-on-a-chip in understanding the mechanisms of toxicity and the regulation of chemicals. 

A true “essential”
If you are in need of an up-to-date, all-in-one overview of the biomedical and environmental aspects of toxicology - written by experts, and presented in full color, your search ends here.


Unit I: General Principles of Toxicology

Chapter 1: History and Scope of Toxicology

Chapter 2: Principles of Toxicology

Chapter 3: Mechanisms of Toxicity

Chapter 4: Risk Assessment

Unit II: Disposition of Toxicants

Chapter 5: Absorption, Distribution, and Excretion of Toxicants

Chapter 6: Biotransformation of Xenobiotics

Chapter 7: Toxicokinetics

Unit III: Non-Organ-Directed Toxicity

Chapter 8: Chemical Carcinogenesis

Chapter 9: Genetic Toxicology

Chapter 10: Developmental Toxicology

Unit IV: Target Organ Toxicity

Chapter 11: Toxic Responses of the Blood

Chapter 12: Toxic Responses of the Immune System

Chapter 13: Toxic Responses of the Liver

Chapter 14: Toxic Responses of the Kidney

Chapter 15: Toxic Responses of the Respiratory System

Chapter 16: Toxic Responses of the Nervous System

Chapter 17: Toxic Responses of the Ocular and Visual System

Chapter 18: Toxic Responses of the Heart and Vascular System

Chapter 19: Toxic Responses of the Skin

Chapter 20: Toxic Responses of the Reproductive System

Chapter 21: Toxic Responses of the Endocrine System

Unit V: Toxic Agents

Chapter 22: Toxic Effects of Pesticides

Chapter 23: Toxic Effects of Metals

Chapter 24: Toxic Effects of Solvents and Vapors

Chapter 25: Toxic Effects of Radiation and Radioactive Materials

Chapter 26: Toxic Effects of Plants and Animals

Chapter 27: Toxic Effects of Calories

Unit VI: Environmental Toxicology

Chapter 28: Nanotoxicology

Chapter 29: Air Pollution

Unit VII: Applications of Toxicology

Chapter 30: Ecotoxicology

Chapter 31: Food Toxicology

Chapter 32: Analytical and Forensic Toxicology

Chapter 33: Clinical Toxicology

Chapter 34: Occupational Toxicology

Chapter 35: Regulatory Toxicology

About the Author

Curtis Klaassen

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